Mucura
Petiveria alliacea
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| Also called Anamu, Mucura is a wild, weedy plant that smells like garlic when crushed. It is used widely for many purposes. In South America it has recently been used for its anti-cancerous properties. It is found toxic against brain and hepatic cancer,1 leukemia and lymphoma cells2 and prevents tumors.3 It is used to fight free radicals and enhance immunity.4 It also kills bacteria5 and fungi,6 making it useful against Candida. It has been clinically documented to have hypoclycemic actions.2 Mucura is used for respiratory, gastrointestinal and nervous conditions. It is antispasmodic, anti-inflammatory7 and anti-rheumatic.8 It is used for fevers and children’s colds, dysentery, migraine headaches, skin diseases, and insect bites. |
 Suggested
retail:
 1oz. Liquid Extract Mucura: $9.95
1lb. Bulk Herb Mucura: $19.95
Suggested Use: Liquids: Use 10 drops mixed with water daily as a restorative tonic.
Suggested Use: Tea: 1 tsp loose leaf per 16 oz of boiling water.
Cautions: May potentiate the effect of coumadin, dut to its natural coumarin content.
Contraindications: Do not use while pregnant. People with blood disorders like hemophilia and that take blood-thinning medications should not use this plant without the supervision of a healthcare practitioner.
Ingredients: Extracted in distilled water and 40% organic grain alcohol. Full spectrum powders are in vegi-caps.
More About Mucura
1. Jovicevic, L., et al. “In vitro antiproliferative activity of Petiveria alliacea L. On several tumor cell lines.” Pharmacol. Res. 1993;27(1): 105-106.
2. Ruffa, M. J., et al. “Cytotoxic effect of Argentine medicinal plant extracts on human hepatocellular carcinoma cell line.” J. Ethnopharmacol. 2002; 79(3): 335-339.
3. Rossi, V., et al. “Antiproliferative effects of Peiveria alliacea on several tumor cell lines.” Pharmacol. Rex. Suppl. 1991;22(2): 434.
4. Queiroz, M. L., et al. “Immunomodulatory activities of Petiveria alliaceae L.” Phytother. Res. 1997; 11(3): 251-253.
5. Bienvides, P.J., et al. “Antifungal polysuphides from Periveria alliacea L. “ Phytochemistry 2001: 57(5): 743-747.
6. Caceres, A., et al. “Plants used in Guatemala for the treatment of protozoal infections. I. Screening of activity to bacteria, fungi and American Trypanosomes of 13 native plants.” J. Ethnopharmacol. 1998 Oct; 62(3): 195-202.
7. Germano, D., et al. “Pharmacological assay of Petiveria alliaceae. Oral anti-inflammatory activity and gastrotoxicity of a hydro alcoholic root extract. “ Fitoterapia 1993; 64(5): 459-467.
8. Lopes-Martins, R. A., et al. “The anti-inflammatory and analgesic effects ofa crude extract of Petiveria alliacea L. (Phytolaccaceae).” Phytomedicine 2002; 9(3): 245-248.
2. Cytotoxic effect of Argentine medicinal plant extracts on human hepatocellular carcinoma cell line.
Ruffa MJ, Ferraro G, Wagner ML, Calcagno ML, Campos RH, Cavallaro L.
Facultad de Farmacia y Bioquijmica, Catedra de Virologija, Universidad de Buenos Aires, Capital Federal, Argentina.
J Ethnopharmacol. 2002 Mar;79(3):335-9.
Methanolic extracts from Achyrocline satureioides (Dc.) Lam, Aristolochia macroura Gomez, Lithraea molleoides (Vell.) Engl., Schinus molle L., unlike those from Celtis spinosa Spreng, Chenopodium ambrosioides L., Petiveria alliacea L., and Plantago major L. showed cytotoxic activity against a human hepatocellular carcinoma cell line, Hep G2. Schinus molle L. was the most active (IC50=50+/-7 microg/ml). These results call for further studies of these extracts.
PMID: 11849838 [PubMed - indexed for MEDLINE]
5. Antifungal polysulphides from Petiveria alliacea L.
Benevides PJ, Young MC, Giesbrecht AM, Roque NF, Bolzani VS.
Instituto de Quimica, Universidade de Sao Paulo, C.P. 26077, CEP 05599-970, SP, Brazil.
Phytochemistry. 2001 Jul;57(5):743-7.
Bioactivity-directed fractionation of the CH(2)Cl(2)/MeOH (2:1, v/v) extract of the roots of Petiveria alliacea, using mutant yeast strains of Saccharomyces cerevisiae and fungi Cladosporium cladosporioides and C. sphaerospermum led to the isolation of dipropyl disulphide (1), dibenzyl sulphide (2), dibenzyl disulphide (3), dibenzyl trisulphide (4), dibenzyl tetrasulphide (5), benzylhydroxymethyl sulphide (6) and di(benzyltrithio) methane (7). Of these, 5-7 are new compounds and this is the first report of the natural occurrence of 2 and 3.
PMID: 11397443 [PubMed - indexed for MEDLINE]
8. The anti-inflammatory and analgesic effects of a crude extract of Petiveria alliacea L. (Phytolaccaceae).
Lopes-Martins RA, Pegoraro DH, Woisky R, Penna SC, Sertie JA.
Laboratorio de Farmacologia e Experimentacao Animal, Instituto de Pesquisa e Desenvolvimento (IP&D/CEN), Universidade do Vale do Paraiba, UNIVAP. Sao Jose dos Campos, SP, Brazil.
Phytomedicine. 2002 Apr;9(3):245-8.
Petiveria alliacea L (Phytolaccaceae) is a perennial bush plant that grows widely in Brazil. The roots and leaves of P. alliacea have been used in folk medicine for their antispasmodic, sedative, diuretic and antihelminthic actions. We recently described the anti-inflammatory properties of P. alliacea administered topically and orally in different animal models. In the present study, we investigated the anti-inflammatory activity of a crude lyophilized extract of P. alliacea roots administered to rats with pleurisy. The oral administration of P. alliacea root extract did not significantly reduce the total number of leukocytes at the doses tested. By contrast, the highest dose of extract tested (43.9 mg/kg body wt.) significantly reduced the number of migrating neutrophils, mononuclear cells and eosinophils; the dose of 31.4 mg/kg body wt. also reduced mononuclear cell migration. The P. alliacea root extract also showed a significant analgesic effect in the experimental model used. The results of this study provide a basis for the use of P. alliacea extracts in popular folk medicine, but further studies are necessary to elucidate the mechanism of its anti-inflammatory and analgesic actions.
PMID: 12046866 [PubMed - indexed for MEDLINE]
Disclaimer: Statements on this page have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information on this publication should not be used as medical advice. Data prvided for research and professional use only.
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